What is dyspepsia?
Dyspepsia often manifests as pain in the upper abdomen. It may include symptoms such as bloating, burping, a burning sensation, pain and nausea. Dyspepsia can also be associated with a marked feeling of fullness following meals, or even with vomiting.
What is gastritis?
Gastritis is an inflammation of the gastric mucosa. In gastritis, the pepsinogen II biomarker level in blood is elevated. Gastritis can be induced by a Helicobacter pylori infection or an autoimmune condition. Testing positive for Helicobacter pylori is an independent risk factor for both gastric cancer and peptic ulcer disease (PUD).
What is atrophic gastritis?
In atrophic gastritis, chronic inflammation results in disappearance of the specific glandular cells in gastric mucosa. This impairs the output of gastric acid, which is closely reflected by the biomarker concentrations of the GastroPanel® test. Decreased (lost) secretion of gastric acid and intrinsic factor (IF) from the gastric mucosa is a risk factor for Vitamin B12- and micronutrient deficiency. Atrophic gastritis is also associated with a significantly increased risk of gastric cancer.